MOTS-c – Mitochondrial-Derived Peptide (MDP) Research Compound
Compound Name: MOTS-c (Mitochondrial-Derived Peptide)
Classification: Research Peptide – Mitochondrial-Derived Peptide (MDP)
Description:
MOTS-c is a synthetic mitochondrial-derived peptide composed of 16 amino acids and encoded within mitochondrial DNA. In controlled laboratory research environments, MOTS-c is widely studied for its role in mitochondrial signaling, cellular energy regulation, and metabolic pathway modulation. Due to its unique origin and signaling characteristics, MOTS-c has become an important research tool for investigating mitochondrial communication with the nucleus and peptide-mediated regulation of cellular homeostasis.
In laboratory and in-vitro model systems, researchers utilize MOTS-c to examine pathways related to metabolic balance, cellular stress response, muscle-related signaling, and mitochondrial adaptation. Its involvement in energy-regulating networks and mitochondrial signaling cascades makes MOTS-c particularly relevant in research focused on metabolism, cellular resilience, and mitochondrial biology.
Selected Research References:
- Lee C et al., Cell Metabolism (2015)
– MOTS-c promotes metabolic homeostasis and regulates energy balance in cellular models. - Kumagai H et al., American Journal of Physiology – Endocrinology and Metabolism (2021)
– MOTS-c reduces signaling associated with muscle atrophy in experimental models. - Zheng Y et al., Frontiers in Endocrinology (2023)
– Review of MOTS-c as a mitochondrial-derived peptide involved in metabolic and endocrine signaling.
Disclaimer:
This product is intended for laboratory research use only (RUO).
Not for human consumption. Not for therapeutic, diagnostic, agricultural, or veterinary use.









