TB-500 – Thymosin Beta-4 Active Fragment Research Peptide
Compound Name: TB-500 (Thymosin Beta-4 Fragment)
Classification: Research Peptide – Thymosin Beta-4 Active Fragment
Description:
TB-500 is a synthetic research peptide representing the active fragment of thymosin beta-4, a naturally occurring intracellular protein involved in actin regulation and cellular structural dynamics. In controlled laboratory research environments, TB-500 is widely studied for its role in peptide-mediated signaling, cytoskeletal organization, and cellular migration pathways.
In experimental research models, TB-500 is frequently examined for its involvement in cellular repair signaling, actin-binding processes, and molecular mechanisms associated with cell movement and structural adaptation. Due to its relevance in intracellular signaling networks, TB-500 is commonly utilized in in-vitro and biochemical studies focused on cellular communication, tissue modeling, and peptide-regulated regulatory pathways.
Scientific References:
- Bock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas F Jr, Olson EN, Srivastava D.,
International Immunopharmacology, 2023; 116:109741 –
Thymosin beta-4 denotes new directions towards developing regenerative biological models
- Kim J, Jung Y.,
Vitamins and Hormones, 2016; 102:121–149 –
Thymosin beta 4 as a potential regulator of hepatic stellate cells
- Zeng PM, Sun XY, Li Y, Wu WD, Huang J, Cao DD, Qian PJ, Ju XC, Luo ZG.,
Stem Cell Reports, 2025; 20(9):102601 –
Thymosin beta 4 as a regulatory target identified using human brain organoid models
Disclaimer:
This product is intended for laboratory research use only (RUO).
Not for human consumption. Not for therapeutic, diagnostic, agricultural, or veterinary use.










